Pediatric genitourinary tumors
نویسندگان
چکیده
منابع مشابه
Pediatric Genitourinary Oncology
Tumors of the kidney, bladder, prostate, testis, and adrenal represent a large part of the adult urologic practice, but are relatively infrequent in children. The natural history and management of these tumors in the pediatric age is different from that of the adults. As result of the successful work of several clinical trial groups in recent decades, there has been a significant improvement in...
متن کاملManagement of advanced genitourinary tumors.
The management of advanced genitourinary tumors is rapidly evolving thanks to the clinical availability of several targeted drugs with different mechanisms of action. Among clinicians, in-depth knowledge of all the aspects of the disease, together with the capacity to interpret and accurately correlate clinical data and imaging findings, are strongly needed. Moreover, the optimization of treatm...
متن کامل20 - Pediatric Genitourinary and Renal Disorders
The full complement of nephrons is present at birth, although newborn nephrons are heterogeneous in glomerular size and proximal tubule length. Anatomy and function mature postnatally. Although fetal urine is excreted into the bladder by 10 to 11 weeks of gestation, the ability to conserve and excrete sodium, concentrate urine, and reabsorb substrates such as glucose evolves to maturity over th...
متن کاملVaccine and Cancer Therapy for Genitourinary Tumors
Immunotherapy for human cancer has remained in the experimental stage for more than a century. This lengthy duration reflects as much the scope of failures in the area as it does the continuous and remarkable expansion of understanding of immune responses and hosttumor interaction. Immunotherapy for human cancer has largely focused on immunization with peptides or whole antigens, intact tumor c...
متن کاملRole of STAT3 pathway in genitourinary tumors
The STAT3 is often dysregulated in genitourinary tumors. In prostate cancer, STAT3 activation correlates with Gleason score and pathological stage and modulates cancer stem cells and epithelial-mesenchymal transition. In addition, STAT3 promotes the progression from carcinoma in situ to invasive bladder cancer and modulates renal cell carcinoma angiogenesis by increasing the expression of HIF1α...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Opinion in Oncology
سال: 2009
ISSN: 1040-8746
DOI: 10.1097/cco.0b013e328329f201